Products

 

Although frozen tissue arrays have so many advantages over paraffin-embedded tissue arrays, there are not many companies can provide frozen array products and services. The following is some information about companies and institutions that are focusing on developing frozen tissue array techniques and providing frozen tissue array products and/or services.

 

 

 

Product Name Frozen Tissue Array
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Product Description Tissue array or tissue microarray from US Biomax includes normal, malignant or metastatic formats. Tissue arrays and Tissue microarrays can be used to validate clinical relevance of potential biological targets in the development of diagnostics, therapeutics and study new protein markers and genes. Tissue array (tissue microarray or so called tissue-chips) contains protein, RNA, or DNA molecules, thus provides high throughput platforms for the rapid analysis of molecular markers associated with disease diagnosis, prognosis and therapeutics in patients. US Biomax also provides custom tissue array as well as services of immunohistochemistry (IHC) staining and In situ hybridization (ISH) on tissue array or tissue microarray.
Specification  
Vendor Information US Biomax, Inc.
223 Forest Ave.
Rockville, MD 20850, USA
www.biomax.us
Toll-Free Number: 800-935-1357
Telephone Number: 301-637-4734
Customer Service: info@biomax.us

 

 

Product Name Frozen Tissue Array
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Product Description IMGENEX Histo-Array™ tissue array slides are a simple, powerful, inexpensive, yet highly efficient method for expression analysis or localization studies of molecular targets at the DNA, RNA or protein level. Over ninety different human or animal tissue array slides are available, with tissue samples densities ranging from 24 to 146 spots per slide, corresponding to tissue sample sizes of 4mm to 1mm. Slides are available with different cancerous, normal, normal adjacent, or diseased tissues of different organs as well as matched tissue samples for certain slides (when noted). Each slide includes patient data on all tissue samples including age, sex, diagnosis, and any applicable staging codes.
Specification  
Vendor Information Imgenex
Flintkote Avenue, Suite E
San diego, CA, 92121
Tel: (858) 642 0978 Toll free: (888) 723 4363
Tech Support: (858) 642 0978
Customer Service: (858) 642 0978
Fax: (858) 642 0937
Website: www.imgenex.com
Email: info@imgenex.com

 

 

Product Name Tissue Microarray (TMA)
Product Description Advances in molecular medicine and biology have fundamentally changed biomedical research strategies. The rate of discovery of new genes involved in cancer and other diseases has increased heavily. Evaluation of the clinical importance of promising candidate genes is optimally performed on histological sections of diseased and non-diseased patient tissues. This not only allows a distinction of positive and negative cases, but also a definition of positive cell types and the subcellular localization of the gene product in question. However, using traditional methods of molecular pathology, such studies would lead to a massive workload in involved laboratories. This is not only because of the high number of candidate genes but also because hundreds or better thousands of tissue samples, optimally with attached follow-up data, must be analyzed in order to yield statistically sound results. Moreover, the analysis of multiple genes resulted in a critical loss of precious tissue material since the number of conventional tissue sections that can be taken from a tumor block does usually not exceed 200 - 300.

To overcome the limitations of conventional tissue analysis, we developed the tissue microarray (TMA) technology in a collaborative project with the laboratory of Olli Kallioniemi (at that time located at the National Human Genome Research Institute in Bethesda).
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Vendor Information